HEXARELIN

What Is Hexarelin

Hexarelin Acetate, also alternatively known as examorelin, is a small synthetic peptide that belongs to the growth hormone secretagogue class (GHS).

It is composed of just six amino acids. The chemical sequence of this growth hormone-releasing peptide (GHRP) is His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2. Being highly compact in structure makes it more stable as well as effective in terms of its functioning in the body.

The reported benefits of Hexarelin are substantial:

Stimulates Muscle Growth.
Rapid Weight Loss.
Improves Strength & Flexibility.
Faster Recovery.
Improves Sleep & Overall Well-Being.

How Does It Work

The primary function of hexarelin is to trigger the release of growth hormone from the anterior pituitary gland. Hexarelin follows multiple courses of action to achieve this purpose.

Hexarelin mimics the action of a naturally occurring hormone called ghrelin. Ghrelin is mainly synthesized in the stomach, and it travels via the bloodstream to bind with the growth hormone secretagogue receptor (GHS-R1a) located in the hippocampus.

This subsequent binding stimulates a wide array of physiological pathways such as the release of growth hormone (GH), protecting cardiomyocytes, regulating body weight, and development of the musculoskeletal system.

Hexarelin also binds with growth hormone secretagogue receptor (GHS-R1a) similar to ghrelin to initiate a phospholipid-dependent protein kinase (PKC) signaling pathway. This leads to the amplified release of growth hormone (GH) due to the coordinated action of the hypothalamus as well as the pituitary gland.

Hexarelin is also known to limit the release of somatostatin, also sometimes referred to as growth hormone-inhibiting hormone (GHIH). This leads to higher serum levels of growth hormone (GH).

The availability of growth hormone secretagogue receptor (GHS-R1a) in the peripheral organs like the heart, bones, adrenal gland, and digestive tract means that hexarelin can also trigger a localized effect. Particularly, the binding of hexarelin with cardiac receptors called CD36 is a growing area of research.

Hexarelin stimulates other endocrine pathways such as ACTH to cause the release of prolactin as well as cortisol.

Where Can I Buy It?

Being not so common, it is easy to fall into scams of buying pseudo hexarelin.

For 100% genuine product at a very reasonable price go here.

Benefits Of Hexarelin

As a growth hormone-releasing peptide (GHRP), hexarelin ensures an organic growth hormone release (GH).

It stimulates the growth of new muscle fibers. This leads to the development of lean muscle mass by bulking up muscles as well as enhancing body strength.

As hexarelin binds to the CD36 receptors located on blood cells, it greatly improves cardiovascular functioning by maintaining normal cardiac parameters such as left ventricular ejection fraction (LVEF), cardiac output, and stroke volume, and decreasing the peripheral resistance in the blood vessels.

This helps athletes meet the physical realms needed to boost their overall performance.

Hexarelin-induced release of growth hormone (GH) also burns down body fat, thereby causing weight loss.

This peptide improves overall skeletal health. This is done by making joints more flexible and making tendons, joints, and ligaments grow healthy. Hexarelin stimulates the growth of new muscle fibers. This leads to the growth of lean muscle mass by bulking up muscles as well as enhancing body strength.

This musculoskeletal growth makes the individual more resistant to injuries.

The optimal release of growth hormone due to hexarelin causes growth and proliferation around wounds and injuries so that the recovery process is quick yet effective.

Besides, it is also hypothesized to improve sleep quality to considerable levels by setting up natural sleep rhythms.

Usage in Bodybuilding

Hexarelin, like the majority of other peptides, works by promoting natural human growth hormone synthesis and release. This leads to more amino acid recruitment in the muscle fibers and increased protein synthesis, thus helping you gain muscle mass and strength.

For this purpose, the studied dose is 200-300 mcg/day. It is best to avoid eating before and after 1 hr of the peptide administration.

Is It Legal?

Check the laws of your country to determine if Hexarelin is legal or not in your area!

Who Should Use It?

Owing to the tremendous effects observed in cardiovascular health, anybody with a history of cardiovascular diseases such as myocardial infarctions and arrhythmias can take Hexarelin. This is because hexarelin is seen to minimize fibrous accumulation.

Bodybuilders aiming to build up muscles can also take Hexarelin. Anyone wishing to have a quicker recovery process can also take it.

Athletes wishing to boost their performance in their respective games can consider hexarelin usage after seeing all the benefits.

How To Use

Just like most other peptides, hexarelin is also available as a dry powder in the vial (a glass container). Once you have purchased hexarelin, you need to mix it with bacteriostatic water, depending on your dosage guidelines.

You need to inject it subcutaneously, inserting the needle just under the skin and not in the muscle. Generally, the abdominal area is seen as an ideal place to inject it. Subcutaneous injection of hexarelin is seen to achieve maximum effects on the user.

If you are afraid of needles, you can take hexarelin orally as well, with the surety of experiencing similar benefits as a subcutaneous injection.

Forms Of Hexarelin

Hormonal therapies are usually more effective in injectable forms. So, I would personally recommend taking the injectable form.

When you make a purchase, you will get a vial in which there will be hexarelin powder. The powder, once mixed with the sterile water, will give you the injectable ready form.

Surprisingly, hexarelin tablets are also available in some areas. This makes it more user-friendly as a wide variety of people can consume hexarelin. But we still highly recommend the injectable form as we know it works better.

General Dosage Guide

Being illegal in many areas means that there exist no set guidelines for the users but considering all the medical research done so far, an ideal dosage is devised.

200mcg-300mcg is advised to be the daily intake of an individual. The optimal results are often seen in people who administer hexarelin subcutaneously 2-3 times a day, with each dose comprising approximately 100 mcg.

Small administrations are often advised because this stimulates the release of growth hormone (GH) at more frequent intervals. Hence, this sets up a natural timer within a short period.

If you are taking hexarelin orally, you can take two tablets in a day, with each around 200mcg.

One of the important interpretations from existing research is that a higher dosage doesn’t seem to impact you significantly.

Cycling

To see optimal results, avoid eating anything before and after 1 hour of administration.

It is generally consumed for straight 12 to 16 weeks. Prominent benefits such as muscle building, fat loss, and quick recoveries are usually achieved during this period.

Once one cycle is complete, take a break of 25 to 30 days. You may start your new cycle for approximately 3 months to maintain the physical changes that the peptide helped you to achieve.

How To Stack

There are many possibilities for stacking Hexarelin with other substances for optinal performance and results.

We recommend you speak with an experienced professional about this to determine what is best to help you reach your specific goals.

Summary

The primary function of Hex is to trigger the release of growth hormone from the anterior pituitary gland. It follows multiple courses of action to achieve this purpose.

It mimics the action of a naturally occurring hormone called ghrelin. Ghrelin is mainly synthesized in the stomach, and it travels via the bloodstream to bind with the growth hormone secretagogue receptor (GHS-R1a) located in the hippocampus.

It also binds with the growth hormone secretagogue receptor (GHS-R1a) similar to ghrelin to initiate a phospholipid-dependent protein kinase (PKC) signaling pathway. This leads to the amplified release of growth hormone (GH) due to the coordinated action of the hypothalamus as well as the pituitary gland.

It is also known to limit the release of somatostatin, also sometimes referred to as growth hormone-inhibiting hormone (GHIH). This leads to higher serum levels of growth hormone (GH).

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Human Growth Hormone (HGH)

HGH helps to maintain, build, and repair healthy tissue in the brain and other organs. This hormone can help to speed up healing after an injury and repair muscle tissue after exercise. This helps to build muscle mass, boost metabolism, and burn fat. HGH is also said to benefit the quality and appearance of the skin.

Human Growth Hormone for Bodybuilding

Human growth hormone (HGH) is associated with increased fat loss and enhanced cosmetic muscle growth. Bodybuilders may inject human growth hormone to achieve a more muscular appearance. However, most of the increase in muscle mass is actually due to fluid retention, not actual muscle growth. There are also risks associated with the use of human growth hormone.

Because of a perceived advantage to muscle growth and strength, bodybuilders and athletes who are tempted to take performance-enhancing drugs and supplements like steroids have taken HGH in order to gain an athletic advantage, or for rapid, cosmetic muscle growth.

Because HGH taken orally can be broken down by digestion, HGH is injected when used as a supplement drug. HGH is also promoted as an agent for rejuvenation for aging people who want to look and perform younger.

Side Effects

The following (but rare) side-effects of injected HGH have been reported with excessive and prolonged abuse:

Muscle or joint pain
Suppression of pituitary/hypothalamus gland function
Swelling of body tissues (edema)
Carpal tunnel syndrome (wrist nerve pain)
Elevated blood glucose levels

Expert Assessment

The National Strength and Conditioning Association (NSCA) in its 2009 review, concluded this about HGH:

“Human growth hormone increases lean body mass within weeks of administration; however, some of this change is within the water compartment and not in body cell mass. Human growth hormone is sometimes administered as a single agent, but often it is used in combination with androgens. Combined administration of HGH and resistance training is associated with maximal gains in lean body mass, muscle size, and voluntary strength in men compared with resistance exercise alone.

CJC-1295 (DAC)

HOW CJC-1295 WORKS IN THE BODY

CJC-1295 offers many benefits to the body, including:

Increased growth hormone secretion and IGF-1 Levels with no increase in prolactin

Increased Body Weight and Length through increased protein synthesis

Increased Muscle Growth

Increased Bone Density

Improved Immune Function

Improved Cognition and Memory

Increased Collagen Production

Increased Fat Loss

Increased Cellular Repair and Regeneration

CJC-1295 also promotes slow wave deep sleep, which is responsible for the highest level of muscle growth and memory retention and rejuvenation.

CJC 1295: GHRH & DAC

GHRH (growth hormone releasing hormone) is produced in the hypothalamus. Its pulsatile release from the hypothalamus triggers a pulsatile release of GH from the pituitary gland. GHRH has a very short half-life of only a few minutes (half-life = the time required to remove half of the substance from the blood. The shorter the half-life, the more rapidly the substance is removed from the body, and the less its effect on the body).

The first 29 amino acids of GHRH is the active segment. They are available as a manufactured peptide called Sermorelin. Sermorelin was further modified to increase its half-life to 30 minutes. This is called CJC 1295. CJC-1295 was further modified by adding DAC (Drug Affinity Complex) to it. DAC binds to a blood protein called albumin, which increases its half-life to 8 days. It is called CJC 1295 + DAC. CJC 1295 can also be compounded in a non-DAC form which mimics a more normal physiologic GH spike each night.

The longer half-life from the DAC binding to albumin means injections are only required once or twice per week. However, the long half-life and relatively constant blood level provide a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiological. This can decrease the GH pulse amplitude which will result in decreased GH tissue stimulation.

CJC-1295 (DAC) Effectiveness

Chart A below shows the increase in muscle building IGF-1 that occurs from varying doses of CJC-1295 (DAC). You will note that the 250 mcg dose reaches significantly higher levels and we have found that this dosing protocol works best. It is the “sweet spot” for most people in terms of economy, efficiency and safety!

Chart B above shows the large increase in IGF-1 levels over a 7 day period.

CJC-1295 (DAC) Half Life

The half life, or time it takes for the compound to be reduced to half of it’s original dose is reflected in the chart below:

This leads us to the final question…

CJC-1295 (DAC) Dosing

The sweet spot we have found with CJC-1295 (DAC) administration seems to be 250 mcg, once per week. People may think doing more would be even more beneficial, and it might, but to a limited extent. Not only are there diminishing returns from larger doses, but larger doses also increases the chance for side effects. What we have found is that 250 mcg per week is the sweet spot before there are diminishing returns. It’s cost-effective, gives more bang for your buck, plus it decreases chance of side effects. We feel 250 mcg, once per week, for most people is definitely the “sweet spot”!

Using CJC 1295 Safely

It is recommended when using a long-acting CJC molecule to have ‘hormone holidays’ of three months to allow the pituitary to ‘recover’. During the holidays, Sermorelin is used daily instead of CJC-1295 (DAC).

The ‘hormone holidays’ may also minimize the risk of GH resistance developing. This resistance, or insensitivity, may occur via antibodies forming that bind to and inactivate GH, or by a decreased number of GH receptors on tissues (down-regulation). These are theoretical concerns as no long-term studies have been undertaken to clarify the issues.

Side effects of CJC-1295 are rare, but may include injection site reactions (irritation, erythema, induration, pain, itching), headache, diarrhea, vasodilation (flushing, warmth, transient hypotension), nausea, abdominal pain.

Questions about CJC-1295 (DAC) or peptide therapy? Contact us today!

HGH (Somatropin)

You may have heard people say Somatropin is good for bodybuilding. People say the same about human growth hormone (HGH). When you hear either option mentioned people are talking about the same thing.

There is a good chance you already know this, so please forgive us for making such an obvious statement. However, many people do not know, especially those who are new to bodybuilding, so we thought we’d try to clear up the confusion right from the start.

The Benefits of Additional Growth Hormones

Human Growth Hormone is one of your primary anabolic hormones. It is responsible for much of the growth spurt you experience during your teenage years. Generally, people who exhibit higher than average growth hormone production during these years are both taller and have a higher muscle mass than others. In fact, HGH improves all of the following:

Muscle Mass
Bone Strength
Fat Reduction
Recovery
Libido
Mood
Sleep
Skin

With all those positives, it’s a shame that you get such a sharp decline of HGH by your mid-twenties. Of course, your body has reached its adult size so there is no need for such a huge amount…but more would be beneficial. Especially for muscle-builders and people wanting to burn fat more easily as well as for any of the above benefits to be honest.

Human Growth Hormone (HGH) is a peptide hormone that is known for stimulating the growth and regeneration of cells. It is a vital hormone for a person, helping to grow until becoming an adult. Then helping with a lot of different things throughout adulthood and elder ages. HGH is extremely important and is therefore prescribed to children with stunted growth. Sometimes to elder people who need to improve the quality of their life.

HGH is prescribed to adults who are suffering from HGH deficiency (which can be due to a number of reasons). In the end, HGH is extremely important, this is a protein hormone having endocrine functions in both animals and humans. Without enough HGH levels, a person cannot live a normal life having many nasty symptoms.

Since HGH is a Growth Hormone, there’s no need to mention the importance of HGH in bodybuilding.

The peptide hormone is used in the medical world for various purposes, and it is also used in the non fitness world for its anti aging properties. But is very popular in the fitness and athletic world too as a very effective (and fairly safe) performance enhancing drug.

HGH and Bodybuilding

HGH has changed the bodybuilding world. Professional bodybuilders from the 1970-1980s were about 100 lbs lighter compared to the professional bodybuilders you see competing on nowadays stages. Anabolic steroids, diets, working out – little has changed since then yet they still managed to pack on almost 100 lbs more weight. How’s that?

Human Growth Hormone has been added to the equation!

This is a compound that is capable of altering genetic limits. It makes the individual grow way more than he would ever be capable of growing without HGH.

HGH Bodybuilding Benefits

As it was earlier mentioned, HGH has a lot of benefits in bodybuilding but one of the main reasons why bodybuilders are running it is, as earlier mentioned, to positively change the genetic capability of the user.

Nonetheless, there are a lot of other benefits too such as strengthening joints and ligaments as well as healing damaged tissue. All of which are extremely important in bodybuilding where super heavy weights are present.

Another thing that HGH is appreciated for in bodybuilding is that this is a natural substance that is not very easily detectable as other performance enhancing drugs (PEDs). Nonetheless, HGH in bodybuilding is still most commonly used along with androgenic and anabolic steroids (AAS) in order to improve athletic performance and to build as many muscles as possible.

HGH in bodybuilding has lots of other benefits such as restoring back age-related deterioration of the body, that’s why it is often considered the “fountain of youth” as it is capable of turning back the biological clock of the body. That’s why it is so popular for other purposes than bodybuilding too.

But Human Growth Hormone is effective for building muscles, strengthening the immune system, reducing body fat (especially at the belly), restoring hair and skin – greatly improving their quality; normalizes blood sugar, cholesterol, increases energy, and greatly improves your sexual life too. It also does a great job in helping to heal and recover from diseases, injuries, and intense training sessions. It improves sleep quality, memory, vision and has cognitive positive effects too. There are lots of other benefits too.

HGH Bodybuilding Dosage

Human Growth Hormone is generally recommended to be administered in a dosage of 1-5 IU a day, being administered with 1 mL insulin syringe (slin pin). The total daily dose is used at the same time of the day either all at once once, or in a split dose administered 2 times daily.

People running HGH for bodybuilding purposes are usually using 4-8 IU daily as this amount is generally enough to improve body composition and grow muscles. Very often, bodybuilders add other compounds with HGH.

Some of the most common ones include Testosterone, Insulin, and many others. It could be T3, Clenbuterol, cutting steroids or bulking ones, injectables, or orals.

Sometimes, bodybuilders go to doses as high as 15 IU daily and even more. But those are dosages that are likely to offer side effects.

A normal cycle length in bodybuilding with HGH is anywhere between 5 and 8 months. But it can be run continuously with an on again, off again type cycle (ie: run M-F with Saturday and Sunday off).

HGH Bodybuilding Side Effects

HGH is taken intravenously and is usually kept in lyophilized powder. Then it is mixed with distilled bacteriostatic water when it must be injected. Is very important to keep it in the refrigerator in case you mix it to avoid side effects.

Is important to remember that HGH is only effective as an injection. HGH pills, tablets, patches, etc. are not going to increase HGH levels.

The abuse of HGH is going to lead to side effects.

Normal administrations are likely to be very well tolerated by most people, especially bodybuilders. But higher dosages are likely to offer side effects such as

carpal tunnel syndrome
increased risks of diabetes
water retention
numbness and tingling of the skin
nerve, muscle, or joint pains
there are others too

There are other side effects like sleepiness. It can interfere with the bodybuilders’ normal schedule of the day. Hypoglycemia is another side effect. Plus, if used for way too long and in way too high dosages it could lead to one of the worst HGH side effect in bodybuilding known as HGH Gut. It is seen in those bodybuilders having 8 pack abs and body fat of under 5% and still having a huge stomach. This is definitely avoidable though by simply not abusing HGH heavily for long periods.

Conclusion

In my honest opinion, if there were but one single bodybuilding (or anti-aging) product I could use for the rest of my life… it would definitely be HGH! It has the least negative side effects potential while giving the most overall benefits of any anabolic out there. The good vs bad profile of HGH is definitely vastly in favor of it being “good” compared to most any other anabolics out there… PLUS with it’s wonderful anti-aging and other benefits…. it’s pretty much a slam dunk no-brainer in my opinion… HGH is it!

ANABOLICA

Bodybuilding & Fitness Information

Category: HGH