Tag: peptides

EPITHALON

Turn Back Time With Epithalon:

Epithalon is a powerful, safe, and effective tetrapeptide that helps your body produce telomerase that protects a body’s cells. This therapy can reverse aging by stimulating your body’s regenerative potential. 

EPITHALON

Epithalon has been called the “fountain of youth” peptide because of its rejuvenating effects. Our patients have also benefited from better sleep and reduced stress with regular Epithalon treatment. It is one of several peptides we offer that might be right for you.

Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.

“THE FOUNTAIN OF YOUTH PEPTIDE”

Epithalon is often regarded as the “fountain of youth” peptide..

Epithalon’s primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones. Younger people produce a relatively large amount of telomerase and longer telomeres. The longer the telomere strands are, the better cell health and replication they provide. However, as people age, the production of telomerase falls and consequently cell replication and health decline. This is the main reason that people age.It also plays a role in regulating metabolism, increasing the sensitivity of hypothalamus to its natural hormonal influences, normalizing the function of the anterior pituitary and regulating the levels of gonadotropins and melatonin in the body.

The implications of what Epithalon can mean to your longevity, fitness, bodybuilding goals as well as improving sleep, appearance and age reduction are obvious!

Benefits of Epithalon Include:

As a result of Epithalon’s effect on telomerase production, the benefits are unique and far-reaching and include:

  • May increase human lifespan by lengthening telomeres in human cells
  • Prevent the effects of Free radicals
  • Promotes Deeper Sleep
  • Delay and prevention of age-related diseases such as cancer, heart disease, and dementia
  • Can act as an antioxidant by reducing lipid oxidation and ROS (Reactive oxygen species) along with normalizing T cell function.
  • Improvement of skin health and appearance
  • Healing of injured and deteriorating muscle cells
  • Has been shown to Restore and normalize melatonin levels in older people who have lost some pineal function due to aging
  • May increases resistance to emotional stress

Epithalon Dosage Calculator and Guide

Insofar as Epithalon is treated as a research chemical, it lacks the type of dosing recommendations that are typically given for officially approved drugs. However, the International Peptide Society has published a dosing protocol based on the extensive work of a renouned professor and his colleagues. This protocol may be administered three times annually for longevity and anti-aging purposes, and is relatively short and more intensive protocol, and is as follows:

Total Required per day: 1mg epithalon

Dosing Schedule: Administer 1mg of Epithalon day. Best taken first thing in the morning.

Duration of Therapy: 10 days

Additional Notes: This protocol is designed to be administered up to three times per year. Each 10-day course should be followed by a pause of at least four months.

CONCLUSION

Epithalon offers a number of benefits that can help combat the symptoms of aging. It also helps with mood, improves sleep, accelerates healing and acts as an antioxidant. 

Numerous studies have shown the importance of telomerase production and telomere rejuvenation in fighting the symptoms of aging. As Epithalon has been shown to increase the production of telomerase which in turn strengthens and lengthens telomeres, this means that Epithalon can play a vital role in decreasing the aging process and thus extend human longevity while improving healing and aiding all fitness / bodybuilding and of course general health efforts.

Contact us if you would like more information about Epithalon!

.

AOD-9604 vs SEMAGLUTIDE

AOD9604 (Growth Hormone Analogue)

AOD9604 is a peptide derived from human growth hormone (HGH) fragment 176-191, itself a derivative of human growth hormone. AOD9604 is a weight loss peptide in the truest sense of the term as it is a targeted fat burner (lipolytic) with limited additional effects. This peptide was specifically developed to maintain the lipolytic (fat burning) fragment of growth hormone without retaining any of the parent molecule’s ability to promote lean body mass accumulation. Research out of Australia shows that AOD9604 increases weight loss 3-fold compared to placebo. It affects beta-3-adrenergic receptors on white fat to boost fat breakdown and may indirectly activate apoptosis (programmed cell death) in white fat cells as well. AOD1604 is one of the most effective peptides for weight loss yet developed, with studies showing as much as a 50% reduction in weight gain over just three-weeks of administration.

This peptide is extremely safe, it is FDA approved, and there are no known health risks associated with AOD 9604 injections, especially when compared to traditional hormone-based weight loss treatments. As with any injection, some common side effects include pain, reddening, and swelling near the injection site.

Semaglutide (GLP-1 Agonist)

Semaglutide is similar in many ways to Liraglutide and is FDA approved for weight management and the treatment of metabolic syndrome. It acts as an agonist of the GLP-1 receptor. Research shows that semaglutide and similar peptides for weight loss work in two different ways. First, Semaglutide can delay gastric emptying and slow intestinal motility to increase feelings of fullness and decrease the rate of rise of blood sugar. Second, Semaglutide can act as a neurotransmitter to reduce the drive to eat in the central nervous system via reductions in the sensation of hunger as well as enhanced feelings of satiety. Semaglutide has been shown to produce a 5% weight loss over 6 months. At one year, average weight loss with semaglutide is 15% of total body weight.

You may know semaglutide as Ozempic, an injectable medication used in people with Type 2 diabetes. Ozempic can help manage blood sugar, and it can also lower the risk of heart attack and stroke if you also have heart disease. You can also find it as an oral pill, called Rybelsus. And Wegovy, a higher-strength version, is approved to help people lose weight.

Semaglutide works by mimicking a gut hormone that causes your pancreas to release insulin, blocks your liver from releasing sugar, and slows down how fast food leaves your stomach. While these actions can be beneficial for Type 2 diabetes and weight loss, they can also cause some side effects.

Some semaglutide side effects can be bothersome and make the medication difficult to tolerate. But the good news is that they usually subside over time. Although rare, there are also some serious side effects to know about. Keep reading to learn more about 10 semaglutide side effects to know about and how to manage them. 

1. Nausea and vomiting

Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even mire common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea.

You’re more likely to experience these side effects with higher doses of semaglutide. That’s why your healthcare provider will raise your dose slowly over a few weeks to minimize these effects. For most people, these side effects should improve over time as your body gets used to the medication.

Eating smaller meals, avoiding high-fat foods, and remaining upright after you eat can also help manage potential nausea and vomiting from semaglutide. But if these side effects are accompanied by severe stomach pain that may or may not spread to your back, get medical attention right away. This could be a signs of pancreatitus, a rare but serious side effect. More on that later.

2. Diarrhea

Diarrhea is another common semaglutide side effect. Around 9% of people taking it for Type 2 diabetes and 30% of people taking it for weight loss reported diarrhea during clinical trials. 

Similar to nausea and vomiting, you’re more likely to experience diarrhea with higher doses of semaglutide. As mentioned above, your healthcare provider will slowly raise your dose over time to minimize this side effect. Constipation can also happen, but it tends to be less common than diarrhea.

3. Stomach pain

Mild stomach pain is another common stomach-related side effect of semaglutide. Similar to nausea, vomiting, and diarrhea, this should subside over time. Using the tips listed above can also help minimize this side effect. 

Severe stomach pain can be a sign of other side effects, like pancreatitis or gallbladder problems (like gallstones). Contact your healthcare provider right away if this develops.

4. Fatigue

Fatigue is a common side effects of Wegovy, affecting 11% of people taking it in clinical trials. Fatigue was also reported in less than 5% of people taking Ozempic, and it wasn’t reported at all with Rybelsus.

Semaglutide works for weight loss by making you feel less hungry. And eating fewer calories may cause you to feel more tired. Feelings of fatigue should subside as your body adjusts to potential changes in your diet. 

5. Low blood sugar

Low blood sugar (hypoglycemia) isn’t very common if you’re taking semaglutide on its own. That’s because it works by telling your body to release insulin in response to a meal specifically. 

But taking semaglutide with other blood sugar-lowering medications, like insulin and sulfonylureas, raises the risk of hypoglycemia. So, your healthcare provider may need to change the dose of these medications when starting semaglutide. 

If you have Type 2 diabetes, it’s important to regularly check your blood sugar levels to help avoid hypoglycemia. You may be advised to have an emergency glucagon or glucagon-like product to raise your blood sugar quickly if severe hypoglycemia happens.

6. Pancreatitis

Although rare, pancreatitis has been reported with semaglutide. If it happens, it can be life-threatening. Seek immediate medical attention if you develop severe abdominal pain, nausea and vomiting, and/or jaundice (yellowing of skin and eyes). 

Let your healthcare provider know before starting semaglutide if you have a history of acute pancreatitis. They may recommend a different medication for you.

7. Gallbladder disease

Gallbladder disease, including gallstones, is possible with semaglutide, but it isn’t common. It was reported in less than 2% of people taking it in clinical trials. 

Symptoms of gallbladder problems include upper stomach pain, fever, and jaundice. You may also notice clay-colored stools. Let your healthcare provider know right away if these develop. 

Talk to your healthcare provider about ways you can avoid gallbladder problems while taking semaglutide. This may include dietary changes and routine physical activity.

8. Kidney damage

Studies have suggested that semaglutide may have some kidney benefits if you have Type 2 diabetes. But in rare cases, kidney damage has also been reported. This is more likely if you have severe nausea, vomiting, and/or diarrhea leading to dehydration. 

Kidney damage is also more common if you already have kidney problems. Taking medications that cause you to get rid of excess water, like diuretics (water pills), also puts you at risk. 

Your healthcare provider may monitor your kidneys if you’re experiencing a lot of stomach-related side effects. Let them know right away if you’re not urinating very much or at all, or notice swelling in your arms or legs.

9. Allergic reactions

Severe allergic reactions to semaglutide are rare, but possible. Call 911 or get immediate medical attention if you have swelling of the face, tongue, or throat, or shortness of breath after your dose. 

Mild allergic reactions can include itching, rash, or redness at the injection site. Stopping semaglutide isn’t always necessary with mild reactions. But make sure to still tell your healthcare provider about your reaction. 

Don’t use oral or injectable semaglutide if you’re allergic to any of their ingredients. And there’s a chance you could have an allergic reaction to semaglutide if you’ve had a reaction to a medication in the same class.

10. Thyroid tumors

Semaglutide has a boxed warning (the strictest warning) from the FDA about a risk of thyroid C-cell tumors. This is because animal studies found that rodents developed thyroid tumors when exposed to GLP-1 agonists. However, human studies have yet to confirm this risk.

Still, you shouldn’t take semaglutide if you or your family have a history of medullary thyroid cancer or multiple endocrine neoplasia (MEN) type 2. Contact your healthcare provider immediately if you notice signs or symptoms of thyroid cancer. These include a lump in your neck, and neck or jaw pain.

All this being said, and speaking strictly for myself (I know there will always be some who will argue to the contrary)… I personally feel it is a no-brainer which one to use if your looking for an EFFECTIVE, PROVEN and SAFE fat burning peptide… In my mind it’s AOD-9604 all the way!

Furthermore, there is a lot of evidence to back up these claims that AOD-9604 is the MUCH safer way to go. And truth be known, most of the resources I have personally checked seem to feel AOD-9604 is actually more effective than Semaglutide overall as well.

Safer… More Effective… You do the math.

I just felt it was important information to bring to you, being that these 2 peptides have gained so much attention in recent months… and these are definitely things you want to consider if you’re looking for such a product to help you with your fat loss goals.

… best of luck to you!

IGF-1 LR3

Introduction

IGF-1 LR3 is a polypeptide long-chain amino acid peptide hormone. Insulin-like Growth Factor (IGF-1 Long-Arginine 3), an 83 amino acid analog of IGF-1, is a highly anabolic hormone released primarily in the liver with the stimulus of growth hormone (HGH).

IGF-1 LR3 plays an important role in cell proliferation, cell-to-cell communication and cell devision.


IGF-1 LR3 is a derivative of IGF-1. Due to its structural adjustment, IGF-1 LR3 has a much longer half-life and results may persist in the bloodstream for up to 120 times longer.

Usage

IGF-1 LR3 is primarily used to increase the biological activity of IGF. When IGF-1 LR3 is mobile in the body, it functions differently in individual types of tissues. For example, in muscle tissue, it forces the muscle to be more sensitive to insulin’s effects, such as the decrease of fat storage.

IGF-1 LR3 is recommended to patients with the following conditions: hormone deficiency in children that results in short stature, adult growth deficiency, short bowel syndrome, short stature due to Turner Syndrome, adult deficiency associated with pituitary tumors or treatment of these tumors and muscle-wasting disease related to HIV/AIDS.

Lypholized (dry powdered) IGF-1LR3 should be kept stored in a freezer, while the reconstituted (liquified) version should be stored in a refridgerator.

Mechanism of Action

IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.

IGF-1 LR3 obstructs the movement of glucose into the body’s cells. This facilitates fat burning and the use of fat in the body for the production of energy. IGF-1 LR3 has a half life in the body for about 20-30 hours and therefore it enhances the growth of muscle for a whole day.

Administration

Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. IGF-1 LR3 can also be administered intra-muscularly.

Before administering IGF-1 LR3, always be sure to use a clean and sterile syringe.

  1. Hold the IGF-1 LR3 vial upright and insert the syringe in the center of the cap.
  2. Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
  3. Before administering the syringe, use alcohol to cleanse the area of skin.
  4. Pinch the skin around the area to be injected, leave about 2 cm on each side.
  5. Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
  6. Depress the plunger fully, until the syringe is empty, and carefully draw out.

Dosage

Dosage Amount:20mcg (0.02mg) – 120mcg (0.12mg)

Dosage Frequency:  Once daily, preferably within 15 minutes of finishing your workout. Follow your injection with a protein / carbohydrate-rich meal or shake.

It is recommended to administer IGF-1 LR3 once daily for six weeks. After six weeks, take approximately 20-40 days off before starting a new course IGF-1 LR3.

Make sure to consume protein with a combination of carbohydrates 15-20 minutes after administering IGF-1/ LR3 for best results.

Side Effects

Some possible side effects of IGF-1 LR3 may include the following: muscle and joint pain, nausea, headaches, hypoglycemia (usually when IGF-1 LR3 is administered in continuous high doses) and may be associated with increased risk of developing some cancers. 

Benefits

  • Enhanced growth hormone levels that are necessary for bone development during childhood and throughout adult life
  • Increase of lean muscle mass
  • Improvement of athletic performance
  • Increased hyperbolas in muscle cells leading to fuller muscle tissues
  • Improvement of muscle recovery and reduced recovery time
  • Reduction of body fat
  • Increased metabolism
  • Regulation of fat storage and prompts fat to bed used for energy production
  • Facilitation of protein synthesis in the body
  • Up-regulation of anti-oxidant benefits and ligament strength

AOD-9064 Peptide

AOD-9064

Try AOD-9064 Peptide if you have been in search of a peptide therapy with all of the medical weight loss benefits and none of the side effects, Peptide AOD-9604 might be the perfect treatment option for you. It has incredible success for weight loss, and is one of the very few FDA-approved peptides.

Keep reading to learn all about this beneficial peptide therapy and how you can unlock its health-hearty powers here at Anabolica.

WHAT IS PEPTIDE AOD-9604?

First and foremost, AOD-9604 Peptide is a modified form of amino acids 176-191 and was originally used as an anti-obesity drug. Once injected, this hormone derivative can stimulate the pituitary gland, which, in turn, speeds up metabolism and burns body fat.

Overall, peptide AOD 9604 greatly improves the results of dietary restrictions and exercise.

HOW DOES AOD-9604 PEPTIDE THERAPY WORK?

This FDA-approved peptide therapy has the unique ability to target areas of the body where there are abnormally high levels of fat, and works wonders when combined with exercising and consuming a lower calorie diet.

AOD-9604 Peptide has two primary methods of regulating body fat:

  • Stimulate lipolysis– the breakdown of fats and lipids via the hydrolyzation of triglycerides into glycerol and fatty acids.
  • Inhibit lipogenesis– the metabolic process that forms fat (even from nonfat foods), which increases the amount of triglycerides in the body.

Furthermore, the amino acids contained in AOD-9604 are the same as those found in the naturally occurring growth hormone (hGH).

WHO CAN BENEFIT FROM AOD-9604?

Researchers have also discovered the benefits of AOD-9604 aren’t limited to fat loss, as it also contains various other regenerative properties that may benefit people with:

  • Osteoarthritis
  • Osteoporosis
  • Hypercholesterolemia
  • Worn cartilage
  • Depression
  • Diabetes
  • Bone damage

One of the most notable benefits that AOD-9604 brings is the ability to help regulate blood sugar and manage insulin levels. This, in turn, will aid inflammation and weight loss. Just like growth hormone, AOD-9604 also enhances muscle-building.

IS AOD-9604 Peptide SAFE?

The U.S. Food & Drug Administration recently assigned Human GRAS status to AOD-9604, meaning it is listed under the Generally Recognized As Safe (GRAS) program. This is a designation that identifies any food additive as safe when used as intended, per the Federal Food, Drug, and Cosmetic Act.

This peptide is extremely safe and there are no known health risks associated with AOD-9064 Peptide injections, especially when compared to traditional hormone-based weight loss treatments.

As with any injection, some common side effects include pain, reddening, and swelling near the injection site. It is important to consult with your physician, or someone knowledgable, regarding medications and supplements you are currently taking for best treatment recommendations.

HOW IS AOD-9604 ADMINISTERED?

When it comes to a standard AOD-9604 treatment plan, there are two administration options:

  • Orally via dissolvable lozenge
  • Subcutaneous injection

Inject the AOD peptide about 30 minutes prior to eating to allow the peptide to fully metabolize and achieve optimal results. Usually only one injection of approx. 250-300 mcg in the morning is necessary, although some choose multiple injections daily.

It is important to follow the dosage instructions provided on the package. If you have any questions or concerns, discuss the administration of your peptide therapy with your healthcare practitioner or similarly knowledgable person.

HOW SHOULD I STORE AOD-9604?

Once the vial is open, reconstituted peptides can break down at high temperatures. Important points to consider when storing AOD-9064 Peptide include:

  • Store at a cool temperature ( 36 to 46°F)
  • Check the manufacturer’s use-by date
  • Take on an empty stomach

Furthermore, the injected peptide will absorb into the bloodstream much quicker when you are in a fasted state. For optimal results, consult with your doctor for the best time and dosage levels if you’re taking other medications and supplements.

WHEN WILL I SEE RESULTS?

Although results will vary depending on the person’s bio-individuality, many people will experience the full benefits of AOD-9064 Peptide within 12 weeks. Often much sooner. A range of personal attributes can affect the quality and significance of results, including:

  • Age
  • Family history
  • Underlying conditions
  • Disease Risks

The most success is typically seen in people who combine injections with a healthy diet and exercise.

Consult someone knowledgable to discuss your protocol to set you up for the ultimate success.

.

Google