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Clenbuterol

Clenbuterol is a fat-burning drug that raises your metabolic rate. Even though it is not approved for use in the U.S., many athletes and bodybuilders use clenbuterol quite effectively to help them reach their fitness goals.‌

Here’s what you need to know about this powerful medication.

What Is Clenbuterol?

Clenbuterol is a drug that is not approved for human use in the U.S. In some countries, it is available by prescription only for people with asthma or other breathing problems. Since 1998, the FDA has allowed clenbuterol for treating horses with asthma. It is not allowed for animals that are used in food production.‌

Clenbuterol is a substance that has steroid-like effects and is classified as a beta2-adrenergic agonist. This means that it stimulates the beta2-adrenergic receptors in your throat. The medicine helps relax your muscles and lungs, making it easier to breathe if you have asthma or another respiratory condition. It can stay in your body for up to 39 hours after you take it.

Clenbuterol for Bodybuilding

However, clenbuterol — also called clen — is used by athletes and bodybuilders for its ability to burn fat. The same receptors that are activated when taking clenbuterol for asthma also help to burn off fat and increase lean muscle mass. Athletes who use clenbuterol daily typically take anywhere from 20 to 120 micrograms per day. Normally this is taken in combination with other performance-enhancing drugs or anabolic steroids. It is wise to start off with a very low dose and slowly ramp up your dosing one day after the other in order to gauge how you will react to the drug.‌

Clenbuterol increases your body temperature through a process called thermogenesis. Once your body temp is up, your metabolism is then primed to burn off more calories. Since fat is stored in the body as energy, your body can use the calories that you already have stored. This can decrease your body fat and lower your overall weight.‌

Because clenbuterol is a bronchodilator, it opens up your airways when you take it. This is helpful for those with asthma. For athletes, this allows them to increase their stamina by having more airflow moving around the body. More oxygen is available, so you can perform harder and better. ‌

Even though it isn’t legal in the US, many athletes and bodybuilders continue to use clen to help them cut weight and increase muscle mass. Many see it as an alternative to anabolic steroids — the drugs that typically come to mind when you think of performance-enhancing substances. It has the reputation of being a “non-steroidal steroid” due to its ability to mimic steroids. Since it isn’t technically a steroid, some athletes see clenbuterol for bodybuilding as a more “natural” approach to building muscle.

Even though it is illegal in certain areas, many athletes still use clen. If you are interested in finding out where you can obtain legitimate, high quality Clenbuterol… send a request for information here. ‌

Fewer androgenic side effects. It’s thought that clenbuterol is more popular than anabolic steroids with female bodybuilders because there are fewer androgenic side effects. Steroids typically cause side effects like an increase in facial hair or the deepening of your voice. Clenbuterol is not known to cause these.‌

Rapid weight loss. As noted, clenbuterol works by raising your metabolism, helping you to burn off fat. One study involved two groups of overweight men who were put on the same strict diet. One group was given clenbuterol and one wasn’t. Over ten weeks, the group who received clenbuterol lost an average of 25.1327 lbs of fat and the control group lost 19.1802 lbs of fat. ‌

Appetite suppression. Many bodybuilders rely on clenbuterol before an upcoming performance or competition to trim off extra fat. A secondary effect of this drug is that it helps curb your appetite so that you take in fewer calories. Not every person experiences this effect, however.

Risks and Side Effects

Many athletes and bodybuilders use clenbuterol for its benefits — but there are several side effects to be aware of.

Some of the most common side effects include:

  • Heart palpitations
  • Tremors
  • Increased heart rate (tachycardia)
  • Lowered blood potassium (hypokalemia)
  • High blood sugar (hyperglycemia)
  • Anxiety 
  • Agitation
  • Sweating 
  • Cardiac arrest
  • Feeling hot or warm
  • Insomnia
  • Muscle cramps

You are more likely to have these side effects if you take higher doses of clenbuterol. Since this drug stays in your body for quite a while, you could have side effects anywhere from one to eight days, but this is found generally in those who jump right into high doses without slowly ramping up their dose over time.

New users of clenbuterol are more likely to experience side effects than people who have previously taken it. If you experience any of these side effects after using clenbuterol, it’s important to immediately stop using it and to get help from a doctor. But you will likely avoid any unpleasant side effects completely if you simply start off with a very low dose… see how you react to the substance… then slowly increase dose each day while monitoring how it effects you. Using clenbuterol in this manner typically will allow you to enjoy all of it’s fat burning and lean muscle building benefits while avoiding any unpleasant side effects.

It is strongly recommended to use LIQUID clenbuterol because it is much easier to dose. You can start off with a few drops and slowly add a drop or two each day to gradually reach a dosing strategy which works best for you!

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ACE-031

ACE-031 peptide is a myostatin inhibitor protein that is produced to imitate a natural receptor involved in controlling muscle mass, strength and function. ACE-031 works as a mysotatin blocker by binding myostatin and additional proteins that regulate the function of myostatin. Myostatin is an important protein that works to prevent the growth and development of muscle cells. 

ACE-031 works by binding myostatin from circulation, which prevents it from binding to its own receptors. These receptors normally function to switch off muscle growth when myostatin is bound, but because the binding is blocked by ACE-031 then muscle growth can continue unrestricted. Human studies using ACE-031 showed increases in lean muscle mass and muscle volume, with beneficial effects on fat and bone biomarkers. Several pharmaceutical companies are also investigating ACE-031 as a treatment for several muscle-wasting disorders, including amyotrophic lateral sclerosis (ALS) and Duchenne muscular dystrophy (DMD). ACE-031 was concluded to be a promising therapeutic approach for treating DMD and myostatin inhibition was shown to be a promising potential therapy in the treatment of ALS.

ACE-031 is packaged into vials as a powder and needs to be completely dissolved in bacteriostatic water. The water should be injected directly (but gently) into the vial. The vial should not be shaken, but can be gently rotated in order to dissolve any remaining powder. ACE-031 1 mg can be dissolved by adding 2 ml of water to provide 1 mg of ACE-031 in every 2 ml of solution. This solution can be injected in one single dose for maximum efficacy or split into several smaller doses. 

ACE-031 Peptide dosage:

  • Mix 2 ml water with each vial of ACE 1mg.
  • Only mix one bottle of each at a time and keep refrigerated once mixed.
  • The most popular dosage is 250-500mcg
  • These doses have led to gains of over 11 pounds of muscle within the short time frame of only 2 months.

The ACE-031 solution should be stored in the fridge for up to one month. For optimal growth of lean muscle mass, ACE-031 dosage can be injected up to 3 mg/kg. Since the half-life of ACE-031 is BETWEEN 10 – 15 days then this dosage should not be exceeded within a two-week period. Subcutaneous or intramuscular injections are optimal when administering these peptides.

Half life

The half life of Ace-031 is 10-15 days.

Treatment with ACE-031 up to 3 mg/kg was shown to be safe and well tolerated in healthy individuals. All side effects that have been reported using ACE-031 at these concentrations are mild and the most common side effect is headache.

If you would like to discuss this fantastic peptide further with a highly experienced expert, feel free to send a message here.

TRIPTORELIN

One shot PCT?

Triptorelin is a peptide hormone that acts as an analog of GnRH (Gonadotropin-Releasing Hormone). GnRH is a naturally occurring hormone produced in the hypothalamus which triggers the production of LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone), which stimulate Testosterone production and spermatogenesis, respectively.

The way Triptorelin works is really simple: It replaces our naturally occurring GnRH production and stimulates the production of LH and FSH. This can be great if a low dose is used but can be devastating when overdosed. Here’s why:

LOW DOSE: Awakens the HPTA after being shutdown during a cycle. It provides the small kick that is necessary to restart endogenous Testosterone and sperm production.

HIGH DOSE: Shuts down the HPTA. High doses are used in criminals, prostate cancer patients and people with hypersexual disorders. High doses cause a sudden dramatic increase in LH and FSH. This increase is so absurd, that the body responds by down-regulating LH and FSH receptors. In other words, the body is shocked by the sudden LH and FSH increase, so it forcibly stops their production, leading to a halt in Testosterone and sperm production.

This can be reversed with SERMs and/or by waiting, which is why criminals who are castrated with Triptorelin need to receive a Triptorelin shot every month.

BENEFITS & SIDE-EFFECTS OF TRIPTORELIN

Besides potential recovery of natural testosterone production, the only benefits of Triptorelin are those that come with having healthy Testosterone and Estradiol levels.

Besides potential castration, the only side-effects of Triptorelin are the side-effects of high Testosterone and Estradiol levels. In other words, if Triptorelin use leads to high Testosterone levels, you will have excess estradiol conversion and all the side-effects that come with having high levels of both hormones (gynecomastia, water retention, moodiness, acne, hair loss, etc…).

TRIPTORELIN PCT PROTOCOL

Triptorelin is often referred to as the “ONE-SHOT PCT”, because there have been plenty of anecdotal reports of men who were completely shut down who managed to permanently restore their natural hormone production with a single Triptorelin shot.

The typical Triptorelin dose for PCT is a single 100mcg (micrograms, not milligrams, very important!) shot. This protocol seems to work well when used after all the compounds used during any given cycle have left the body. Some people advocate for using Tamoxifen or another SERM alongside Triptorelin for at least 14 days, to ensure that there is no dip in LH and FSH production after using Triptorelin.

HGH FRAG 176-191

If you have been in search of a peptide therapy with all of the medical weight loss benefits and none of the side effects, Peptide HGH Frag 176-191 might be the perfect treatment option for you. It has incredible success for weight loss, and is one of the very few FDA-approved peptides.

Keep reading to learn all about this beneficial peptide therapy and how you can unlock its health-hearty powers here at Anabolica.

WHAT IS PEPTIDE HGH Frag 176-191?

First and foremost, peptide HGH Frag 176-191 is a modified form of amino acids 176-191 and was originally used as an anti-obesity drug. Once injected, this hormone derivative can stimulate the pituitary gland, which, in turn, speeds up metabolism and burns body fat.

Overall, peptide HGH Frag 176-191 greatly improves the results of dietary restrictions and exercise.

HOW DOES HGH Frag 176-191 PEPTIDE THERAPY WORK?

This FDA-approved peptide therapy has the unique ability to target areas of the body where there are abnormally high levels of fat, and works wonders when combined with exercising and consuming a lower calorie diet.

Peptide HGH Frag 176-191 has two primary methods of regulating body fat:

  • Stimulate lipolysis– the breakdown of fats and lipids via the hydrolyzation of triglycerides into glycerol and fatty acids.
  • Inhibit lipogenesis– the metabolic process that forms fat (even from nonfat foods), which increases the amount of triglycerides in the body.

Furthermore, the amino acids contained in HGH Frag 176-191 are the same as those found in the naturally occurring growth hormone (hGH).

WHO CAN BENEFIT FROM HGH Frag 176-191?

Researchers have also discovered the benefits of HGH Frag 176-191 aren’t limited to fat loss, as it also contains various other regenerative properties that may benefit people with:

  • Osteoarthritis
  • Osteoporosis
  • Hypercholesterolemia
  • Worn cartilage
  • Depression
  • Diabetes
  • Bone damage

One of the most notable benefits that HGH Frag 176-191 brings is the ability to help regulate blood sugar and manage insulin levels. This, in turn, will aid inflammation and weight loss. Just like growth hormone, HGH Frag 176-191 also enhances muscle-building.

IS PEPTIDE HGH Frag 176-191 SAFE?

The U.S. Food & Drug Administration recently assigned Human GRAS status to HGH Frag 176-191, meaning it is listed under the Generally Recognized As Safe (GRAS) program. This is a designation that identifies any food additive as safe when used as intended, per the Federal Food, Drug, and Cosmetic Act.

This peptide is extremely safe and there are no known health risks associated with HGH Frag 176-191 injections, especially when compared to traditional hormone-based weight loss treatments.

As with any injection, some common side effects include pain, reddening, and swelling near the injection site. It is important to consult with your physician, or someone knowledgable, regarding medications and supplements you are currently taking for best treatment recommendations.

HOW IS HGH Frag 176-191 ADMINISTERED?

When it comes to a standard HGH Frag 176-191 treatment plan, there are two administration options:

  • Orally via dissolvable lozenge
  • Subcutaneous injection

Inject the HGH Frag 176-191 peptide about 30 minutes prior to eating to allow the peptide to fully metabolize and achieve optimal results. Usually only one injection of approx. 250-300 mcg in the morning is necessary, although some choose multiple injections daily.

It is important to follow the dosage instructions provided on the package. If you have any questions or concerns, discuss the administration of your peptide therapy with your healthcare practitioner or similarly knowledgable person.

HOW SHOULD I STORE HGH Frag 176-191?

Once the vial is open, reconstituted peptides can break down at high temperatures. Important points to consider when storing HGH Frag 176-191 include:

  • Store at a cool temperature ( 36 to 46°F)
  • Check the manufacturer’s use-by date
  • Take on an empty stomach

Furthermore, the injected peptide will absorb into the bloodstream much quicker when you are in a fasted state. For optimal results, consult with your doctor for the best time and dosage levels if you’re taking other medications and supplements.

WHEN WILL I SEE RESULTS?

Although results will vary depending on the person’s bio-individuality, many people will experience the full benefits of HGH Frag 176-191 within 12 weeks. Often much sooner. A range of personal attributes can affect the quality and significance of results, including:

  • Age
  • Family history
  • Underlying conditions
  • Disease Risks

The most success is typically seen in people who combine injections with a healthy diet and exercise. Consult someone knowledgable to discuss your protocol to set you up for the ultimate success.

IGF-1 LR3 / PEG-MGF Cycle

How To Cycle IGF-1 LR3 and PEG-MGF

There are many different schools of thought on how to cycle IGF-1 LR3 and PEG-MGF together. The important factor in how to accomplish this effectively relies on proper utilization. Below, we will give you a simple, yet highly effective cycle of these two peptides used together that will give maximum results. You may need to adjust your workout schedule to fit this dosing protocol in order to reap the best results!

The Cycle

Sunday – none (rest day)

Mon – IGF-1 LR3 – 100 mcg (1/2 hr. pre-workout)

Tues – PEG-MGF 200 mcg (rest day)

Wed – IGF-1 LR3 – 100 mcg (1/2 hr. pre-workout)

Thur – PEG-MGF – 200 mcg (rest day)

Fri – IGF-1 LR3 – 100 mcg (1/2 hr. pre-workout)

Sat – PEG-MGF – 200 mcg (rest day)

Note – It is important to take your doses at the same time of day each day. Consistency is key.

Discussion

As you can see there is a definitive method for taking these peptides together, and it will be extremely beneficial for you to follow the dosing and workout schedule as outlined above. This pattern reflects the very nature of how these peptides work, and how they can best augment each other. I highly recommend you follow this exact pattern for best results.

Following the above dosing / workout schedule will allow you to run this cycle for as along as 2 full months effectively!

What Is Needed?

3 Vials – IGF-1 LR3 (1 mg)

3 Vials – PEG-MGF (2mg)

Bacteriostatic Water

Insulin Syringes

(Above protocol at above doses would last a bit over 2 months)

Conclusion

The IGF-1 LR3 and PEG-MGF cycle can be a powerful and highly effective anabolic cycle which can yield significant gains done solo. But to further enhance results, a researcher may also include select Steroids and / or Sarms to this cycle to enhance the effects even further!

For more information on this, or any other product or combination of products, feel free to contact us at any time. We are happy to share knowledge and assist you in whatever way we can.

BPC-157

Repair Damaged Joints and Boost Recovery!

BPC-157 is a peptide that helps alleviate joint pain, improve joint mobility, and boost recovery from injuries. It also increases vascular flow to the tendons and ligaments to increase healing and can also help aid skin burns heal faster and increase blood flow to damaged tissues.

Since BPC-157 is derived from a protein in the stomach, it’s often used to help treat stomach and intestinal conditions including fistulas, ulcers, and inflammatory conditions such as arthritis. BPC-157 has also been shown to help people with organ damage.

It’s also ideal for nagging injuries where the tissue needs to be rejuvenated. It appears to work by accelerating the rate of angiogenic repair. Angiogenesis is a key dynamic process for wound healing as it allows the formation of new blood vessels from old ones and is involved in the organization of a microvascular network.

What are BPC-157’s main benefits?

Studies conducted in rodents and cultured cells have suggested that BPC-157 may support the healing of various tissues, including tendons, joints, nerves, the intestinal tract, the stomach, and skin.

What are BPC-157’s main drawbacks?

BPC-157’s potential drawbacks are uncertain, given lack of human evidence. No clear toxicity or negative side effects have been reported in studies conducted in rodents, but this research is limited.

How does BPC-157 work?

BPC-157 has various possible (potentially overlapping) mechanisms of action, including promoting nitric oxide synthesis, activating cells involved in tissue repair, stimulating the synthesis of growth factors, and inhibiting inflammation.

BPC-157 can be taken orally, topically, or via injection. Oral ingestion of peptides like BPC-157 wouldn’t normally be expected to have a direct effect on tissues outside of the gastrointestinal tract (like tendons and nerves) because peptides aren’t easily absorbed into circulation. However, studies in rodents have suggested that oral ingestion can have systemic effects, meaning that the feasibility of this route of delivery can’t be ruled out.

What is BPC-157?

BPC-157 is a peptide consisting of 15 amino acids. It is derived from a protein found in the stomach. Ingestion or injection of BPC-157 is suspected of enhancing the repair of damaged tissues. And though no clinical data exists to support this, real world use by bodybuilders, athletes and many others indicates it is quite effective.

What else is BPC-157 known as?

Note that BPC-157 is also known as:

  • PL 14736
  • PL-10
  • Bepecin

BPC-157 should not be confused with:

  • TB-500

Dosage informationMedical disclaimer

The closest possible recommended dose is based on rat studies where oral administration showed benefit, as most studies administer the supplement via injection. The oral dose that was effective in rats, 10 μg/kg, is estimated to be equivalent to 1.6 μg/kg, or:

  • 110 μg for a 150lb person
  • 145 μg for a 200lb person
  • 180 μg for a 250lb person

Conclusion

BPC-157, which has greatly increased in popularity, is a peptide used by many bodybuilders, athletes and others for the purpose of accelerating muscle growth, wound healing, injury and organ repair and a host of other physical ailments. Real world application shows definitively that it works well for meeting these goals. And though there is no clinical data available for human consumption dosages… our research has found that 250 mcg seems a very effective dose for the average 180-200 lb male.

PEG-MGF

What is PEG-MGF?

Mechano-Growth Factor (MGF) is an anabolic peptide found in muscle, bone, tendon, neural, and cardiac tissue following periods of increased stress. It is a split variant or isoform of insulin-like growth factor-1 (IGF-1), also known as IGF-1Ec. MGF functions to increase stem cell proliferation in given tissues, allowing for more rapid recovery.

What Forms of PEG-MGF Are Available?

PEG-MGF is available as a subcutaneous injections.

What is the Point of Taking MGF & PEG Together?

mgf

Since MGF has a relatively short half-life (5-7 minutes), MGF is pegylated. Pegylation is the addition of polyethylene glycol (PEG) to the peptide. The addition of the PEG group is a safe and effective way to increase the MGF half-life to 48-72 hours. Conveniently, the PEG group does not bind itself to other substances in the body and is excreted rapidly via urination.

Who can benefit from using Mechano-Growth Factor?

Primarily, MGF is used in conditions requiring anabolic enhancement, and this includes bony and soft tissue repair (e.g., muscle, tendons, ligaments) following workouts or injury, sarcopenia (muscle wasting), stroke, or heart attack. MGF is especially beneficial for individuals requiring enhanced muscle building and recovery following workouts as performed by bodybuilders and other athletes.

Benefits of Mechano-Growth Factor Over Time

Guests have seen benefits in these areas after using PEG-MGF:
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What You Need to Know

PEG-MGF is a safe and effective option for use in patients who are looking to improve recovery and repair through anabolic signaling. PEG-MGF should be used with caution in patients who are prone to  hypoglycemia. Furthermore, patient-specific dosing and injection schedules are vital to avoid unwanted tissue hypertrophy.

PEG-MGF Dosing

Dosing protocols can be effected by several factors. Included in this are your weight, experience with peptides, what other anabolic’s you may be using, and of course personal goals. Typical dosing ranges anywhere from 100 mcg – 500 mcg. We feel that 200 mcg is an effective dose for most people.

Ask an expert if interested in learning more about this highly effective anabolic peptide.

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EPITHALON

Turn Back Time With Epithalon:

Epithalon is a powerful, safe, and effective tetrapeptide that helps your body produce telomerase that protects a body’s cells. This therapy can reverse aging by stimulating your body’s regenerative potential. 

EPITHALON

Epithalon has been called the “fountain of youth” peptide because of its rejuvenating effects. Our patients have also benefited from better sleep and reduced stress with regular Epithalon treatment. It is one of several peptides we offer that might be right for you.

Epithalon (also known as Epitalon or Epithalone) is the synthetic version of the polypeptide Epithalamin which is naturally produced in the pineal gland.

“THE FOUNTAIN OF YOUTH PEPTIDE”

Epithalon is often regarded as the “fountain of youth” peptide..

Epithalon’s primary role is to increase the natural production of telomerase, a natural enzyme that helps cells reproduce telomeres, which are the protective parts of our DNA. This allows the replication of our DNA so the body can grow new cells and rejuvenate old ones. Younger people produce a relatively large amount of telomerase and longer telomeres. The longer the telomere strands are, the better cell health and replication they provide. However, as people age, the production of telomerase falls and consequently cell replication and health decline. This is the main reason that people age.It also plays a role in regulating metabolism, increasing the sensitivity of hypothalamus to its natural hormonal influences, normalizing the function of the anterior pituitary and regulating the levels of gonadotropins and melatonin in the body.

The implications of what Epithalon can mean to your longevity, fitness, bodybuilding goals as well as improving sleep, appearance and age reduction are obvious!

Benefits of Epithalon Include:

As a result of Epithalon’s effect on telomerase production, the benefits are unique and far-reaching and include:

  • May increase human lifespan by lengthening telomeres in human cells
  • Prevent the effects of Free radicals
  • Promotes Deeper Sleep
  • Delay and prevention of age-related diseases such as cancer, heart disease, and dementia
  • Can act as an antioxidant by reducing lipid oxidation and ROS (Reactive oxygen species) along with normalizing T cell function.
  • Improvement of skin health and appearance
  • Healing of injured and deteriorating muscle cells
  • Has been shown to Restore and normalize melatonin levels in older people who have lost some pineal function due to aging
  • May increases resistance to emotional stress

Epithalon Dosage Calculator and Guide

Insofar as Epithalon is treated as a research chemical, it lacks the type of dosing recommendations that are typically given for officially approved drugs. However, the International Peptide Society has published a dosing protocol based on the extensive work of a renouned professor and his colleagues. This protocol may be administered three times annually for longevity and anti-aging purposes, and is relatively short and more intensive protocol, and is as follows:

Total Required per day: 1mg epithalon

Dosing Schedule: Administer 1mg of Epithalon day. Best taken first thing in the morning.

Duration of Therapy: 10 days

Additional Notes: This protocol is designed to be administered up to three times per year. Each 10-day course should be followed by a pause of at least four months.

CONCLUSION

Epithalon offers a number of benefits that can help combat the symptoms of aging. It also helps with mood, improves sleep, accelerates healing and acts as an antioxidant. 

Numerous studies have shown the importance of telomerase production and telomere rejuvenation in fighting the symptoms of aging. As Epithalon has been shown to increase the production of telomerase which in turn strengthens and lengthens telomeres, this means that Epithalon can play a vital role in decreasing the aging process and thus extend human longevity while improving healing and aiding all fitness / bodybuilding and of course general health efforts.

Contact us if you would like more information about Epithalon!

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Human Growth Hormone (HGH)

HGH helps to maintain, build, and repair healthy tissue in the brain and other organs. This hormone can help to speed up healing after an injury and repair muscle tissue after exercise. This helps to build muscle mass, boost metabolism, and burn fat. HGH is also said to benefit the quality and appearance of the skin.

Human Growth Hormone for Bodybuilding

Human growth hormone (HGH) is associated with increased fat loss and enhanced cosmetic muscle growth. Bodybuilders may inject human growth hormone to achieve a more muscular appearance. However, most of the increase in muscle mass is actually due to fluid retention, not actual muscle growth. There are also risks associated with the use of human growth hormone.

Because of a perceived advantage to muscle growth and strength, bodybuilders and athletes who are tempted to take performance-enhancing drugs and supplements like steroids have taken HGH in order to gain an athletic advantage, or for rapid, cosmetic muscle growth.

Because HGH taken orally can be broken down by digestion, HGH is injected when used as a supplement drug. HGH is also promoted as an agent for rejuvenation for aging people who want to look and perform younger.

Side Effects

The following (but rare) side-effects of injected HGH have been reported with excessive and prolonged abuse:

  • Muscle or joint pain
  • Suppression of pituitary/hypothalamus gland function
  • Swelling of body tissues (edema)
  • Carpal tunnel syndrome (wrist nerve pain)
  • Elevated blood glucose levels

Expert Assessment

The National Strength and Conditioning Association (NSCA) in its 2009 review, concluded this about HGH:

“Human growth hormone increases lean body mass within weeks of administration; however, some of this change is within the water compartment and not in body cell mass. Human growth hormone is sometimes administered as a single agent, but often it is used in combination with androgens. Combined administration of HGH and resistance training is associated with maximal gains in lean body mass, muscle size, and voluntary strength in men compared with resistance exercise alone.

CJC-1295 (DAC)

HOW CJC-1295 WORKS IN THE BODY

CJC-1295 (DAC) offers many benefits to the body, including:

Increased growth hormone secretion and IGF-1 Levels with no increase in prolactin

Increased Body Weight and Length through increased protein synthesis

Increased Muscle Growth

Increased Bone Density

Improved Immune Function

Improved Cognition and Memory

Increased Collagen Production

Increased Fat Loss

Increased Cellular Repair and Regeneration

CJC-1295 also promotes slow wave deep sleep, which is responsible for the highest level of muscle growth and memory retention and rejuvenation.

Questions about this or any other peptide therapy? 

Contact Us

CJC 1295: GHRH & DAC

GHRH (growth hormone releasing hormone) is produced in the hypothalamus. Its pulsatile release from the hypothalamus triggers a pulsatile release of GH from the pituitary gland. GHRH has a very short half-life of only a few minutes (half-life = the time required to remove half of the substance from the blood. The shorter the half-life, the more rapidly the substance is removed from the body, and the less its effect on the body).

The first 29 amino acids of GHRH is the active segment. They are available as a manufactured peptide called Sermorelin. Sermorelin was further modified to increase its half-life to 30 minutes. This is called CJC 1295. CJC-1295 was further modified by adding DAC (Drug Affinity Complex) to it. DAC binds to a blood protein called albumin, which increases its half-life to 8 days. It is called CJC 1295 + DAC. CJC 1295 can also be compounded in a non-DAC form which mimics a more normal physiologic GH spike each night.

The longer half-life from the DAC binding to albumin means injections are only required once or twice per week. However, the long half-life and relatively constant blood level provide a constant stimulus for GH release from the pituitary through the GHRH receptor, which is not physiological. This can decrease the GH pulse amplitude which will result in decreased GH tissue stimulation.

CJC-1295 (DAC) Effectiveness

Chart A below shows the increase in muscle building IGF-1 that occurs from varying doses of CJC-1295 (DAC). You will note that the 250 mcg minimum dose reaches significantly higher levels and we have found that this dosing protocol works best. It is a “sweet spot” for most people if economy is a factor. It also an efficient and safe protocol! 1-2 mg per week is optimal!

CJC-1295 (DAC)

Chart B above shows the large increase in IGF-1 levels over a 7 day period.

CJC-1295 (DAC) Half Life

The half life, or time it takes for the compound to be reduced to half of it’s original dose is reflected in the chart below:

This leads us to the final question…

CJC-1295 (DAC) Dosing

The sweet spot we have found with CJC-1295 (DAC) administration seems to be 1–2 mg once or twice weekly. People may think doing more would be even more beneficial, and it might, but to a limited extent. Not only are there diminishing returns from larger doses, but larger doses also increases the chance for side effects. What we have found is that 1–2 mg per week is the sweet spot before there are diminishing returns. It’s cost-effective, gives more bang for your buck, plus it decreases chance of side effects.

Use It Safely!

It is recommended when using a long-acting CJC molecule to have ‘hormone holidays’ of three months to allow the pituitary to ‘recover’. During the holidays, Sermorelin is used daily instead of CJC-1295 (DAC).

The ‘hormone holidays’ may also minimize the risk of GH resistance developing. This resistance, or insensitivity, may occur via antibodies forming that bind to and inactivate GH, or by a decreased number of GH receptors on tissues (down-regulation). These are theoretical concerns as no long-term studies have been undertaken to clarify the issues.

Side effects are rare, but may include injection site reactions (irritation, erythema, induration, pain, itching), headache, diarrhea, vasodilation (flushing, warmth, transient hypotension), nausea, abdominal pain.

Questions about this or any other peptide therapy? 

Contact Us

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